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RMRC Publications

  1. Borhani N, Izadi I, Motahharynia A, Sheikholeslami M, Gheisari Y*. DrugTar Improves Druggability Prediction by Integrating Large Language Models and Gene Ontologies, bioRxiv. 2024 

  2. Sheikholeslami M, Mazrouei N, Gheisari Y,  Fasihi A, Irajpour M, Motahharynia A*. DrugGen: Advancing Drug Discovery with Large Language Models and Reinforcement Learning Feedback. bioRxiv. 2024 

  3. Roointan A, Ghaeidamini M, Yavari P, Naimi A, Gheisari Y, Gholaminejad A*. Transcriptome meta-analysis and validation to discovery of hub genes and pathways in focal and segmental glomerulosclerosis. BMC Nephrol. 2024 

  4. Eshraghi Y, Abedi M, Gheisari Y*. Proteomics to metabolomics: A new insight into the pathogenesis of hypertensive nephropathy. Kidney Blood Press Res. 2023

  5. Roointan A, Shafieizadegan S, Ghaeidamini M, Gheisari Y, Hudkins KL, Gholaminejad A. The Potential of Cardiac Biomarkers, NT-ProBNP and Troponin T, in Predicting the Progression of Nephropathy in Diabetic Patients: A Meta-Analysis of Prospective Cohort Studies. Diabetes Res Clin Pract. 2023

  6. Moein S, Ahmadbeigi N, Adibi R, Kamali S, Moradzadeh K, Nematollahi P, Nardi NB, Gheisari Y*. Regenerative potential of multinucleated cells: bone marrow adiponectin-positive multinucleated cells take the lead. Stem Cell Res Ther. 2023 

  7. Kiyanpour F, Abedi M, Gheisari Y*. miR‑802‑5p is a key regulator in diabetic kidney disease. J Res Med Sci 2023

  8. Borzou P, Ghaisari J*, Izadi I, Eshraghi Y, Gheisari Y*. A novel strategy for dynamic modeling of genome-scale interaction networks. Bioinformatics. 20231

  9. Adibi R, Moein S, Gheisari Y*. Zoledronic acid targets chemo-resistant polyploid giant cancer cells. Sci Rep. 2023 

  10. Adibi R, Moein S, Gheisari Y*. Cisplatin-Resistant Ovarian Cancer Cells Reveal a Polyploid Phenotype with Remarkable Activation of Nuclear Processes. Adv Biomed Res. 2023 

  11. Roointan A, Gholaminejad A, Shojaie B, Hudkins KL, Gheisari Y. Candidate MicroRNA Biomarkers in Lupus Nephritis: A Meta-analysis of Profiling Studies in Kidney, Blood, and Urine Samples. Mol Diagn Ther. 2022 

  12. Gholaminejad A, Moein S, Roointan A, Mortazavi M, Nouri R, Mansourian M, Gheisari Y*. Circulating β2 and α1 microglobulins predict progression of nephropathy in diabetic patients: a meta‐analysis of prospective cohort studies. Acta Diabetol. 2022

  13. Masoudi-Sobhanzadeh Y, Gholaminejad A, Gheisari Y, Roointan A*. Discovering driver nodes in chronic kidney disease-related networks using Trader as a newly developed algorithm. Comput Biol Med. 2022

  14. Hojjati F, Roointan A*, Gholaminejad A, Eshraghi Y, Gheisari Y. Identification of key genes and biological regulatory mechanisms in diabetic nephropathy: Meta-analysis of gene expression datasets. Nefrologia. 2022

  15. Motahharynia A, Moein S*, Kiyanpour F, Moradzadeh K, Yaqubi M, Gheisari Y. Olfactory receptors contribute to progression of kidney fibrosis. NPJ Syst Biol Appl. 2022 

  16. Borhani N, Ghaisari J*, Abedi M, Kamali M, Gheisari Y*. A deep learning approach to predict inter-omics interactions in multi-layer networks. BMC Bioinformatics. 2022 

  17. Abedi M, Marateb HR, Mohebian MR, Aghaee-Bakhtiari SH, Nassiri SM, Gheisari Y*. Systems biology and machine learning approaches identify drug targets in diabetic nephropathy. Sci Rep. 2021 

  18. Gholaminejad A, Gheisari Y, Jalali S, Roointan A*. Comprehensive analysis of IgA nephropathy expression profiles: identification of potential biomarkers and therapeutic agents. BMC Nephrol. 2021 

  19. Gholaminejad A, Roointan A, Gheisari Y*. Transmembrane signaling molecules play a key role in the pathogenesis of IgA nephropathy: a weighted gene co-expression network analysis study. BMC Immunol. 2021 

  20. Samadi M, Gheisari Y*. A nurturing environment for teaching molecular biology to medical students. J Educ Health Promot. 2021 

  21. Roointan A, Gheisari Y, Hudkins KL, Gholaminejad A*. Non-invasive metabolic biomarkers for early diagnosis of diabetic nephropathy: Meta-analysis of profiling metabolomics studies. Nutr Metab Cardiovasc Dis. 2021 

  22. Moein S, Nickaeen N, Roointan A, Borhani N, Heidary Z, Javanmard SH, Ghaisari J*, Gheisari Y*. Inefficiency of SIR models in forecasting COVID-19 epidemic: a case study of Isfahan. Sci Rep. 2021

  23. Moein S, Adibi R, da Silva Meirelles L, Nardi NB, Gheisari Y*. Cancer regeneration: Polyploid cells are the key drivers of tumor progression. Biochim Biophys Acta Rev Cancer. 2020 

  24. Moein S, Moradzadeh K, Javanmard SH, Nasiri SM, Gheisari Y*. In vitro versus in vivo models of kidney fibrosis: Time‑course experimental design is crucial to avoid misinterpretations of gene expression data. J Res Med Sci 2020

  25. Moradzadeh K, Nassiri SM, Gheisari Y*. Valproic acid restores the down-regulation of SDF-1 following kidney ischemia; experimental validation of a mathematical prediction. Res Pharm Sci. 2020 

  26. Samadi M, Tabibian F, Moradzadeh K, Nassiri SM, Gheisari Y*. Evaluating the effect of remote ischemic preconditioning on kidney ischemia–reperfusion injury. Journal of Research in Medical Sciences 2020

  27. Kiyanpour F, Abedi M, Gheisari Y*. A systematic integrative approach reveals novel microRNAs in diabetic nephropathy. Journal of Research in Medical Sciences 2020

  28. Nickaeen N, Ghaisari J*, Moein S, Gheisari Y*. Bifurcation Analysis of a modular model of Embryonic Kidney Development. Biosystems. 2020 

  29. Nickaeen N, Ghaisari J*, Heiner M, Moein S, Gheisari Y*. Agent-based modeling and bifurcation analysis reveal mechanisms of macrophage polarization and phenotype pattern distribution. Sci Rep. 2019 

  30. Abedi M, Fatehi R, Moradzadeh K, Gheisari Y*. Big Data to Knowledge: Common Pitfalls in Transcriptomics Data Analysis and Representation. RNA Biol. 2019 

  31. Moradzadeh K, Gheisari Y*. The analysis of a time-course transcriptome profile by systems biology approaches reveals key molecular processes in acute kidney injury. J Res Med Sci 2019

  32. Moradzadeh K, Moein S, Nickaeen N, Gheisari Y*. Analysis of time-course microarray data: Comparison of common tools. Genomics. 2019

  33. Rabieian R, Moein S, Khanahmad H, Mortazavi M, Gheisari Y*. Transcriptional noise in intact and TGF-beta treated human kidney cells; the importance of time-series designs. Cell Biol Int. 2018 

  34. Aghayan HR, Arjmand B, Ahmadbeigi N, Gheisari Y, Vasei M*. Draft of Iranian National Guideline for Cell Therapy Manufacturing. Arch Iran Med. 2017

  35. Fatehi R, Khosravi S, Abedi M, Salehi R, Gheisari Y*. Heterozygosity analysis of polycystic kidney disease 1 gene microsatellite markers for linkage analysis of autosomal dominant polycystic kidney disease type 1 in the Iranian population. J Res Med Sci 2017

  36. Rabieian R, Abedi M, Gheisari Y*. Central nodes in protein interaction networks drive critical functions in transforming growth factor beta-1 stimulated kidney cells. Cell J. 2017 

  37. Moein S, Javanmard SH, Abedi M, Izadpanahi MH, Gheisari Y*. Identification of appropriate housekeeping genes for gene expression analysis in long-term hypoxia-treated kidney cells. Adv Biomed Res. 2017

  38. Gheisari Y, Ahmadbeigi N. Mesenchymal Stem Cells and Endothelial Cells: A Common Ancestor? Arch Iran Med. 2016 

  39. Gheisari Y, Vasei M, Shafiee A, Soleimani M, Seyedjafari E, Omidkhoda A, Langroudi L, Ahmadbeigi N*. A Three-Dimensional Scaffold-Based System for Modeling the Bone Marrow Tissue. Stem Cells Dev. 2016 

  40. Heidary Z, Ghaisari J, Moein S, Naderi M, Gheisari Y*. Stochastic Petri Net Modeling of Hypoxia Pathway Predicts a Novel Incoherent Feed-Forward Loop Controlling SDF-1 Expression in Acute Kidney Injury. IEEE Trans Nanobioscience. 2016 

  41. Abedi M, Gheisari Y*. Nodes with high centrality in protein interaction networks are responsible for driving signaling pathways in diabetic nephropathy. PeerJ. 2015